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London sarcoma service

Royal National Orthopaedic Hospital NHS Trust

University College London Hospitals NHS Foundation Trust

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our approach & expertise

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research & clinical trials

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currently open trials

ANNOUNCE - A randomized, double-blind, placebo-controlled, phase 3 trial of olaratumab plus doxorubicin vs. placebo plus doxorubicin in patients with advanced or metastatic STS

Bone Sarcoma CTC study - Optimisation of circulating tumour cell detection in bone sarcomas

CASPS - A Phase II Trial of Cediranib in the Treatment of Patients with Alveolar Soft Part Sarcoma (CASPS). This trial is testing a new drug cediranib that has already shown promising results in a small number of patients with alveolar soft part sarcoma. Cedirinib works by inhibiting growth of blood vessels in tumours.

CREATE - a cross-tumoral phase II trial exploring crizotinub (PF-02341066) in patients with advanced tumours induced by casual alterations of ALK and/or MET

EE 2012 - an international randomised controlled trial for the treatment of newly diagnosed Ewing's sarcoma family of tumours

Enliven - A Double-blind, Randomized, Placebo-controlled Phase 3 Study of Orally Administered PLX3397 in Subjects with Pigmented Villonodular Synovitis or Giant Cell Tumor of the Tendon Sheath

EQMR - Evaluating the feasibility of using whole body T1 mapping MRI in the assessment of differing tumour types and assessing response and changes in tumours to systemic oncological therapy.

GOG-0277 -A phase III randomised trial of gemcitabine plus docetaxel followed by doxorubicin versus observation for uterus-limited, high grade uterine leiomyosarcoma

IMRIS - A phase II study of intensity modulated radiotherapy (IMRT) in primary bone and soft tissue sarcoma

Kindred Study - The International Sarcoma Kindred Study: a global multi-site prospective cancer genetics study

MEMOS - A Mechanistic Study Of Mifamurtide (MTP-PE) In Patients With Metastatic And/Or Recurrent Osteosarcoma

Paragon - a phase II study of aromatase inhibitors in women with potentially hormone responsive recurrent/metastatic gynaecological neoplasms

rEECUr - International Randomised Controlled Trial of Chemotherapy for the Treatment of Recurrent and Primary Refractory Ewing Sarcoma

RMS 2005 - A protocol for non-metastatic rhabdomyosarcoma. This study is investigating the use of chemotherapy in the treatment of children and teenagers with rhabdomyosaroma that has not spread around the body.

STRASS -  A phase III randomised trial of preoperative radiotherapy plus surgery versus surgery alone for patients with retroperitoneal sarcoma

Sometimes there may be other trials open - it is always worth asking your doctor.