Researchers at UCLH have been awarded funding from Cancer Research UK for a national study of Intensity Modulated Radiotherapy (IMRT) in Sarcoma.  Dr Beatrice Seddon will be the lead investigator for the trial.

IMRT is an advanced radiotherapy technique that has the potential to reduce the radiation dose to normal body tissues in the treatment area. This effect may have an impact on reducing immediate and long-term side effects of radiotherapy. It could also allow higher doses of radiation to be given safely to bone sarcomas in challenging areas such as the pelvis and spine. 

The IMRiS trial will evaluate the value of IMRT in different groups of sarcoma patients:

• In patients with soft tissue sarcomas of the limbs, it is anticipated that IMRT will reduce the long-term side effects of treatment, and the trial will measure the incidence of side effects at different time points.
• In patients with bone sarcomas of the pelvis or spine, the trial will look at the radiation doses that can be achieved with IMRT, as well as the side effects from treatment.

Sarcoma centres across the UK will take part in this trial which is scheduled to open in June 2015.

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